Considered, consultant-led care for treatment-resistant depression at The Burlington Clinic, Harley Street
Treatment-Resistant Depression · Harley Street

Treatment-resistant depression

When the treatments you have tried have not been enough, it does not mean you are out of options. A fresh, consultant-led look can open a different way forward.

Consultant-Led In-Person or Online
Consultant Psychiatrist–led GMC-registered Harley Street & Online
Understanding It

When depression won't lift

Treatment-resistant depression describes depression that has not responded fully to standard treatments, despite giving them a proper try. Research suggests this is more common than many people realise, affecting around a third of those living with depression. It is not a personal failing, and it is not the end of the road. Often it simply means the approach needs to change.

A Different Look

Why it may not have worked yet

01

The full picture

Symptoms can have overlapping causes. A careful reassessment sometimes reveals something that changes the plan.

02

Tried properly

Dose, duration and combination all matter. Reviewing what has been tried, and how, often points to a better next step.

03

A wider range

Beyond first-line treatments, other approaches may be appropriate, considered carefully and individually.

How We Help

A considered next step

Care begins with an unhurried assessment with Dr. Saal, taking a full history of what you have experienced and what has already been tried. From there, you will have a plan built around you. That may mean revisiting and refining existing treatments, adding talking therapy, or, where clinically appropriate, considering specialist options such as IV infusion therapy. Any specialist treatment is a considered step, offered only after individual assessment. It is a treatment rather than a cure, and suitability differs from one person to the next.

What to Expect

Seen the way that suits you

At Harley Street

  • Private appointments in a calm consulting room.
  • Consultant-led care from our specialist team.
  • In a discreet setting in the medical district of London.

Online

  • The same consultant-led care, by secure video.
  • Appointments that fit around your day, wherever you are.
  • A private, confidential space to talk.
The Process

Simple, steady steps

01

Enquiry

Get in touch and arrange a first appointment at a time that suits you.

02

Assessment

A thorough consultation with Dr. Saal, including a full history of what has been tried.

03

Your plan

A personalised plan, which may refine current treatment, add therapy, or consider specialist options.

04

Review

Ongoing review with Dr. Saal, adjusting as you progress.

Good to Know

Common questions

Do I need a GP referral?

No referral is needed to book a private consultation. With your consent, we can liaise with your GP.

I have already tried several treatments. Can you still help?

Yes. A fresh assessment looks at the whole picture, including what has been tried and how, to find options that may not yet have been explored.

Will I need medication?

Not necessarily. Any plan is discussed with you fully, and medication is only considered where it's clinically appropriate.

Are appointments in person or online?

Both are available, at 10 Harley Street or by secure video wherever you are.

If you are struggling to cope, or having thoughts of suicide, please reach out now. You can call Samaritans free on 116 123, or NHS 111, at any time.

Take the First Step

There is a way forward

Your first step is an unhurried consultation with Dr. Saal. Session fees are shared on enquiry.

Request a consultation